Experiments in Search of Genetic Material
Experiments in Search of Genetic Material: Overview
This Topic covers sub-topics such as DNA, Griffith Experiment, Hershey and Chase Experiment, Avery Experiment, Chemical Composition of DNA, Properties of Genetic Material and, Evidence of DNA as Genetic Material
Important Questions on Experiments in Search of Genetic Material
The series of experiments done by F. Griffith involved which of the following bacterium:
MacLeod, McCarty and Avery determined that R strain bacteria transforming into S strain bacteria because of:
Experiments of Griffith on mice explained the phenomenon of:
Arrange the following biological discoveries in the correct chronology from the earliest to the latest.
i. British biochemist Frederick Sanger introduces his 'plus and minus' method for DNA sequencing.
ii. American scientists Walter Gilbert and Allan Maxam introduce their method of DNA sequencing using chemical processes to terminate DNA strands.
iii. Swiss physician Friedrich Miescher discovers and isolates DNA
iv. Canadian-American researchers Oswald Avery and Colin Munro MacLeod, along with American geneticist Maclyn McCarty, working on experiments on pneumococcal bacteria, establish that DNA could transform the properties of cells.
v. American biologist James Watson and English physicist Francis Crick discover the double helix when solving the three-dimensional structure of DNA, working from crystallographic data produced by Rosalind Franklin and Maurice Wilkins.
A student isolated a new virus which is able to infect E. coli. The following experiment has to follow to confirm the hereditary material of new virus.
Match the following:
| List - I | List - II | List-III | |||
| (A) | Discovery of genetic material | () | Transforming principle | () | Conjugation |
| (B) | Chromatium | () | Derive energy from the oxidation of an inorganic substance | () | Obtain carbon from the atmosphere |
| (C) | Conservative process | () | Capture light energy | () | S. pneumoniae |
| (D) | Beggiotoa | () | Donor retains a copy of genetic material | () | Obtain carbon from |
The correct answer is :
Arrange the following aspect of a double stranded molecule with the sequence in ascending order
A) Number of phosphodiester bond
B) Number of bonds
C) Number of total pyramidines
Match the following lists:
| List - I | List - II | ||
| Erwin Chargaff | Transforming principle | ||
| Frederick Griffith | Nuclein | ||
| Alfred Hershey | Ratio between and and that between and are constant, each equals one | ||
| Colin MacLeod | Biochemical nature of transforming principle | ||
| as the genetic material that is passed from virus to bacteria | |||
The correct match is
Which of the following is the distance between two nucleotides of a polynucleotide strand of DNA?
Which of the following is an incorrect statement?
The biochemical characterisation of 'transforming substance' in Griffith's experiment was done by
To prove that is the genetic material which radioactive isotope were used by Hershey and Chase in their experiments?
Which of the following is incorrect according to Griffith's experiment?
Hershey and chase used which virus to prove that DNA is the genetic material and infective part of virus?
Match the Column I with Column II and select the correct option:
|
Column – I |
Column – II |
|
A. Transformation |
(i) Miescher |
|
B. Reverse central dogma |
(ii) Griffith |
|
C. Nuclein |
(iii) Wilkins |
|
D. X–ray diffraction data |
(iv) Temin and Baltimore |
Fill in the blank:
The unequivocal proof that DNA is the genetic material came from the experiment of ____.
From the options, find out the unequivocal proof that DNA is the genetic material came from the experiment that utilised
Due to which characteristic feature, Griffith could distinguish the two strains of Streptococcus pneumoniae?
Read the following statements regarding the transformation experiment and choose the correct statement(s):
A. It was performed by F. Griffith on Streptococcus pneumoniae.
B. It proved that DNA is the genetic material.
C. Avery, Macleod, and McCarty worked to determine the biochemical nature of the transforming principle.
D. Dnase inhibits the transformation.
Who discovered the transforming material in Griffith’s experiment was DNA?
